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Viagra: Maximum Capacity at High-Altitudes?; FDA Actions.
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The levels of circulating tumor cells at baseline and at the first follow-up visit after the initiation of therapy were the most significant predictors of progression-free and overall survival in women with metastatic breast cancer.
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Screening techniques for the early detection of breast cancer in women at high risk commonly include clinical breast examination and conventional mammography. In the current report from a single institution, the added value of annual magnetic resonance imaging (MRI) and ultrasound were examined. Among 236 women with BRCA1 or BRCA2 gene mutations, twenty-two cancers were detected.
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YKL-40 may represent a novel marker for the detection of early stage ovarian cancer. YKL-40 levels in early stage patients may also predict disease recurrence and survival. The use of YKL-40 in detection of early stage ovarian cancer deserves further investigation.
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Routine pelvic and para-aortic lymph node dissection is not necessary in the majority of women with ovarian low malignant potential tumors.
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Accurate staging is essential for providing appropriate therapy for small-cell lung cancer because patients with disease confined to one hemi-thorax (limited stage) are treated quite differently that those with more extensive disease at presentation. In the current report from a single institution, the value of pretreatment PET was determined. Of 24 patients considered by conventional imaging studies to have limited disease, two were correctly upstaged on the basis of the PET.
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The Prostate Cancer Outcomes Study reports health-related quality-of-life findings 5 years after diagnosis on a cohort of prostate cancer patients who had either initial radical prostatectomy or external beam radiation therapy. Patients who were treated with radiation were more likely to experience rectal discomfort and hemorrhoidal pain, whereas those who were treated surgically suffered a somewhat greater rate of urinary incontinence.
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